What is Ondansetron? This cohort study examines the association between ondansetron exposure during pregnancy and the risks of spontaneous abortion, stillbirth, and major congenital
A new study from Brigham and Women’s Hospital finds that pregnant women taking the common anti-nausea medication ondansetron during the first
jogc
Food and Drug Administration's new labeling system for safety of medications during pregnancy and breastfeeding no longer uses alphabetical ratings (A
1 Despite lack of United States Food and Drug Administration approval for indicated use in pregnancy
For instance, the Centers for Disease Control and Prevention (CDC) indicates that for most of the birth defects looked at in a 2018 study, researchers found
A 2018 study found that taking ondansetron (Zofran®), a medicine used to treat nausea and vomiting, during early pregnancy did not appear to increase the chance of having a
2018;320(23):2429-2437
It was designed originally for chemotherapy-induced nausea and vomiting
Food and Drug Administration
Ondansetron in Pregnancy and the Risk of Congenital Malformations: A The data source, study design, and analytic methods were the same as described in our previously published evaluation of oral ondansetron
, Reproductive Toxicology (2014) 1349 Infants of women who took ; ondansetron in early pregnancy
Nausea and vomiting of pregnancy (NVP) is a common condition that affects approximately 75% of pregnant women
If the previous pregnancy category guidelines were to be applied to elbasvir/grazoprevir, a category of “B” may have been appropriate
Medical, social, and legal implications of treating nausea and vomiting of pregnancy
Although ondansetron has been evaluated for the treatment of nausea and vomiting of pregnancy, current guidelines note data related to fetal safety are conflicting (ACOG 2018); ondansetron is generally
A 2018 study published in the Journal of the American Medical Association specifically addressed ondansetron use during the first trimester of pregnancy and the link to oral clefts
In July 2019, the European Medicines Agency (EMA) Pharmacovigilance Risk Assessment Objective: To study the association between ondansetron exposure during pregnancy and the risks of spontaneous abortion, stillbirth, and major congenital malformations
hoarseness
About 90% of pregnant women have symptoms of nausea and/or vomiting (Fejzo et al
Prophylaxis
Ondansetron is increasingly used off label to treat nausea and vomiting during pregnancy