The latest Journal Gazette & Times-Courier in a digital E-edition format
Extended-release Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension)
Metoprolol is available as two different salts: metoprolol tartrate and metoprolol succinate
5 mg/kg in rats (a dose that is only 0
The half life of Metoprolol is between 3 and 7 hours
Metoprolol may be taken on its own or along with other medications used to manage high blood pressure or heart failure
Specifically, it is used alone or with other medicines to improve blood flow and Extended-release products are given once daily
Metoprolol tartrate (Lopressor) is short-acting and often taken several times a day, whereas metoprolol succinate (Toprol XL) is long-acting and typically taken once a day
, 11 times, on a mg/m 2 basis, the daily dose of 450 mg in a 60-kg patient
com on Feb 15, 2023
It works by affecting the response to nerve impulses in certain parts of the body, like the heart
For a drug to be totally eliminated from your system it takes around 5
Metoprolol succinate extended-release, in dosages of 100 to 400 mg once daily, produces similar β1-blockade as conventional metoprolol tablets administered two to four times daily
Metoprolol succinate extended- release tablet administered once a day, and immediate release metoprolol administered once to four times a day, provided comparable total beta1-blockade over 24 hours (area under the beta1-blockade versus time curve) in the dose range 100–400 mg