3 years, 23
Oxybutynin is used to treat symptoms of an overactive bladder, such as incontinence (loss of bladder control) or a frequent need to urinate
These common side effects of oxybutynin may affect more than 1 in 100 people: feeling dizzy, sleepy, or a spinning sensation (vertigo) diarrhoea or being sick (vomiting) constipation
Also not recommended for people with heart disease, dementia, liver or kidney disease, an enlarged prostate, myasthenia gravis Here’s why that’s bad: Out of the six antimuscarinic medications used for OAB, oxybutynin is linked with the highest rates of cognitive decline in the elderly
Methods: We conducted a cohort study by using the diabetes dataset of the Taiwan
9%)
9% in the oxybutynin group, 4
In contrast, other studies have found no link between anticholinergic medication use and dementia risk
Several studies have reported that oral oxybutynin has a significant negative effect on cognitive function in healthy adults ≥60 years of age A recent white paper published by the Society for Urodynamics, Female Pelvic Medicine, and Urogenital Reconstruction (SUFU) advises of an increased risk of dementia associated with the prolonged use of anticholinergic medications in patients with overactive bladder (OAB) and provides practical clinical guidance for reducing that risk
Oxybutynin oral
The association was stronger for The oxybutynin label recommends caution in patients with pre‐existing dementia treated with cholinesterase inhibitors because it can exacerbate symptoms
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